Chemical and Biological Studies of Zingiber Phillipseae Rhizomes Extract
نویسندگان
چکیده
A novel flavonoidic compound, 3,5-dihydroxy-4’,7-dimethoxyflavone, has been isolated from the rhizomes of Zingiber phillipseae. The dichloromethane extract of this species was shown to be non-toxic with LC50 for acute and toxic levels at 9,732 ppm and 562 ppm, respectively. The extract showed higher antioxidant activity than the standard (butylated hydroxytoluene, BHT) but lower than dichloromethane extract of Zingiber officinale. It showed significant activity against Staphylococcus aureus and Escherichia coli with minimum inhibitory concentration (MIC) at 200μg/ml and 225 μg/ml respectively. Both extracts were found negative toward Candida albicans.
منابع مشابه
Anti-platelet aggregation and vasorelaxing effects of the constituents of the rhizomes of Zingiber officinale.
In the present study, the chemical investigation of the bioactive fractions of the rhizomes of Zingiber officinale has resulted in the identification of twenty-nine compounds including one new compound, O-methyldehydrogingerol. Some of the isolates were subjected into the evaluation of their antiplatelet aggregation and vasorelaxing bioactivities. Among the tested compounds, [6]-gingerol and [6...
متن کاملChemical Composition and Mineral Contents of Zingiber officinale and Alpinia allughas (Zingiberaceae) Rhizomes
Abstr Zingiber officinale and Alpinia allughas are used in Chinese, Ayurvedic and Tibb-Unani herbal medicines all over the world for a wide array of ailments. Presenet study was carried out to determine chemical composition and minerals contents of Zingiber officinale and Alpinia allughas rhizomes. Samples were collected from local retail market of Faisalabad, Pakistan. Moisture, ash, crude fib...
متن کاملBioassay Screening of the Essential Oil and Various Extracts of Fruits of Heracleum persicum Desf. and Rhizomes of Zingiber officinale Rosc. using Brine Shrimp Cytotoxicity Assay
In the present work, the bioassay screening of the essential oil and various extracts of two plants including fruits of Heracleum persicum Desf. and rhizomes of Zingiber officinale Rosc. have been studied with brine shrimp test. There is only one report about cytotoxicity of H. sphondylium in literature and so H. persicum has been used as second selection. At first essentials oil and various ex...
متن کاملBioassay Screening of the Essential Oil and Various Extracts of Fruits of Heracleum persicum Desf. and Rhizomes of Zingiber officinale Rosc. using Brine Shrimp Cytotoxicity Assay
In the present work, the bioassay screening of the essential oil and various extracts of two plants including fruits of Heracleum persicum Desf. and rhizomes of Zingiber officinale Rosc. have been studied with brine shrimp test. There is only one report about cytotoxicity of H. sphondylium in literature and so H. persicum has been used as second selection. At first essentials oil and various ex...
متن کاملIn Vivo Evaluation of Ethanolic Extract of Zingiber officinale Rhizomes for Its Protective Effect against Liver Cirrhosis
Zingiber officinale is a traditional medicine against various disorders including liver diseases.The aim of this study was to assess the hepatoprotective activity of the ethanolic extract of rhizomes of Z. officinale (ERZO) against thioacetamide-induced hepatotoxicity in rats. Five groups of male Sprague Dawley have been used. In group 1 rats received intraperitoneal (i.p.) injection of normal ...
متن کامل